Is Omicron the new Cowpox?

 kw: medical musings, pandemic, omicron, delta, sars-cov2, covid-19, omicold

These data from Worldometer show Covid-19 cases and deaths from about Memorial Day 2021 to today, January 5, 2022, for the US as a whole. The scale lines on the left represent 250,000 and 500,000 cases per day. Those on the right represent 2,000 and 4,000 deaths per day. The solid lines are 7-day running averages.

Wave 5, mainly from the Delta variant, peaked at about 167,600 cases on Sept. 2, and just over 2,000 deaths on and around Sept. 18, 2021, 2½ weeks later.

Wave 6, transitioning from Delta to Omicron, recently rose through 615,000 daily cases around the turn of the year, but the recent death rate is about 1,200 per day.

Clearly, the Omicron variant is quite different from Delta. The Wave 6 death rate is hard to estimate with the case rates rising so rapidly, but it appears to be in the range 0.1% to 0.25% of known cases. That is very similar to the average death rates for recent strains of influenza. 

The Wave 5 death rate was 1.2% of known cases. A complicating factor is that between 25% and 40% of the cases in Wave 6 are Delta, and it is likely that most of the deaths can be attributed to Delta. I sincerely hope so, because that would mean that Omicron is less than 1/10th as deadly as Delta, maybe less than 1/100th. It may be no deadlier than getting a cold!

It may take a few more weeks for Wave 5 to crest, if it hasn't already. Prior waves took two to three months to crest. A cautious forecast puts the crest in mid-February, with a peak rate of 1.5-2 million new cases per day. The Omicron variant could infect half the US population by the middle of March. If it infects less than that, it will most likely be because the mRNA agents being touted as vaccines provide robust cross-variant protection. About 2/3 (62%) of American adults are "fully vaccinated" (I don't count "booster" shots as adding anything useful), and another 15-20% have had at least one injection. Another thirty million (9%) have recovered from Covid-19; they were "vaccinated by God." That doesn't leave very many "unvaccinated" Americans. This implies something very hopeful!

A little history: The word "vaccine" traces back to the Latin word vaccinus, meaning "cow". The word "vaccination" was coined in 1800 by Edward Jenner to describe his method of injecting people with the virus that causes cowpox, and this protected them from the much deadlier disease smallpox.

Dr. Marty Makary of Johns Hopkins calls the current variant "Omicold," saying its effect is similar to a common cold caused by several other coronaviruses that have been circulating for many years. The Omicron variant, being similar to the Alpha and Delta variants, but much less virulent, is likely to be a "cowpox clone", philosophically speaking. I know twelve people, including my son and his wife, who have contracted Covid-19 during the past month. I presume they all caught the Omicron variant, because all have told me it is like a bad cold: a day or two or three of mostly bed rest, with lots of fluids, had them up and about again, and in another day or so their symptoms were over.

I pray that this pandemic has nearly run its course. The Omicron variant is likely to break the back of more damaging variants. Only time will tell if it will also break the back of the totalitarian impulse shown by many in government who have assumed draconian powers by taking advantage of our fears.